Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,1':4',1''-terphenyl-3,3''-diol | - |
Homo sapiens | |
3,3'-pyridine-2,5-diyldiphenol | - |
Homo sapiens | |
3-[4-(4-hydroxyphenyl)thiophen-2-yl]phenol | - |
Homo sapiens | |
3-[5-(4-hydroxyphenyl)thiophen-2-yl]phenol | - |
Homo sapiens | |
3-[5-(4-hydroxyphenyl)thiophen-3-yl]phenol | - |
Homo sapiens | |
4-[5-(3-hydroxyphenyl)thiophen-2-yl]-2-methylphenol | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
T-47D cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
estrone + NADPH + H+ | - |
Homo sapiens | estradiol-17beta + NADP | - |
? |
Synonyms | Comment | Organism |
---|---|---|
17beta-hydroxysteroid dehydrogenase type 1 | - |
Homo sapiens |
17betaHSD1 | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | dependent on | Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.000046 | - |
at 37°C in phosphate buffer (50 mM) with 20% (v/v) glycerol and 1 mM EDTA | Homo sapiens | 4-[5-(3-hydroxyphenyl)thiophen-2-yl]-2-methylphenol | |
0.000069 | - |
at 37°C in phosphate buffer (50 mM) with 20% (v/v) glycerol and 1 mM EDTA | Homo sapiens | 3-[5-(4-hydroxyphenyl)thiophen-2-yl]phenol | |
0.000077 | - |
at 37°C in phosphate buffer (50 mM) with 20% (v/v) glycerol and 1 mM EDTA | Homo sapiens | 3-[4-(4-hydroxyphenyl)thiophen-2-yl]phenol | |
0.000101 | - |
at 37°C in phosphate buffer (50 mM) with 20% (v/v) glycerol and 1 mM EDTA | Homo sapiens | 3,3'-pyridine-2,5-diyldiphenol | |
0.000151 | - |
at 37°C in phosphate buffer (50 mM) with 20% (v/v) glycerol and 1 mM EDTA | Homo sapiens | 3-[5-(4-hydroxyphenyl)thiophen-3-yl]phenol | |
0.000173 | - |
at 37°C in phosphate buffer (50 mM) with 20% (v/v) glycerol and 1 mM EDTA | Homo sapiens | 1,1':4',1''-terphenyl-3,3''-diol |